Proton Pump Inhibitor–induced Hyperhidrosis: Important but Not Recognized

Not significant but important.

Armstrong and colleagues report the result of a large Phase IIb randomized trial evaluating the effectiveness of a preparation of the Bowman Birk Inhibitor compared with an oral placebo in reversing the extent of oral leukoplakia as measured visually by pathology or a battery of intermediate end points. In this editorial, we review the report of this negative clinical trials result to highlight...

Proton pump inhibitors are not antacids!

Proton pump inhibitors (PPIs) are among the most commonly prescribed drugs in clinical practice. Since the introduction of these potent acid-suppressing agents in the late 80s, they were listed in the Guinness Book of World Records as the most prescribed in human history. Yet, to be effective in inhibiting the proton pump enzyme (H+/K+ ATPase) in the parietal cells, these drugs should be taken ...

Proton Pump Inhibitors (PPIs) and Drug-Induced Hyperhidrosis: A Clinical Case

Objective: To discuss the role of a proton pump inhibitor (pantoprazole) as a cause of night sweats in an older person. Methods: Our case involves a 73 year-old man who experienced night sweats while taking pantoprazole to treat gastroesophageal reflux disease. Results: Night sweats disappeared ten days after ceasing pantoprazole. They recurred two months later, one week after recommencing pant...

Workplace violence in health care: recognized but not regulated.

Workplace violence is one of the most complex and dangerous occupational hazards facing nurses working in today's health care environment. This article includes critiques of the conceptual, empirical, and policy progress of the past decade, a discussion of the need for methodologically rigorous intervention effectiveness research, and a description of a joint-labor management research effort ai...

Proton Pump Inhibitors: Omeprazole